The Peruvian genera of Edrotini (Pimeliinae) are revised. A new genus Pachacamacius Flores & Giraldo gen. nov. with two new species, Pachacamacius aguilari Giraldo & Flores sp. nov. (type species) and Pachacamacius koepckeae Flores & Giraldo sp. nov., is described. Two species originally described in the genus ProhylithusKaszab, 1964 are reassigned to two new monotypic genera: Sechuranus Flores and Giraldo gen. nov. (type species Prohylithus barbatusKaszab, 1964) and Koneus Giraldo and Flores, gen. nov. (type species Prohylithus peruanusKaszab, 1981). This article includes diagnoses for five genera and redescriptions or descriptions, distributional data, habitat records and habitus photographs for six species. A dichotomous key for all 11 Peruvian species of Edrotini, drawings of new species' male genitalic features, and distribution maps are also provided. A discussion of the external morphological characters and male genitalia of the new taxa compared to the genera and species previously described and on endemicity and zoogeography of Peruvian Edrotini is presented.