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1 October 2000 Photochemical and Photobiological Properties of New Bispsoralen Derivatives (Bis[PsCn]PIP, n = 4, 6, 8)
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Abstract

Bispsoralen derivatives possessing two psoralens and one piperazine molecule, 1,4-bis[n′-(8-psoralenoxy) alkyl] piperazine (Bis[PsCn]PIP, n = 4, 6, 8), show high water solubility, efficient intercalation into DNA and good photocrosslinking efficiency of DNA. Bis(PsC4)PIP shows high lethality on bacteriophage T7 and can effectively inhibit the amplification of DNA by stopping the polymerase chain reactions in a short period of irradiation time.

Sung Ki Kim, Han Oh Park, and Sang Chul Shim "Photochemical and Photobiological Properties of New Bispsoralen Derivatives (Bis[PsCn]PIP, n = 4, 6, 8)," Photochemistry and Photobiology 72(4), 472-476, (1 October 2000). https://doi.org/10.1562/0031-8655(2000)072<0472:PAPPON>2.0.CO;2
Received: 25 May 2000; Accepted: 1 July 2000; Published: 1 October 2000
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