Some fasciolariid species of the eastern Pacific Ocean from western Mexico to Alaska are discussed, with the description of the new genus Araiofusus gen. nov. and nine new species: Fusinus edjanssi sp. nov. from Cedros Island, Pacific coast of Baja California to San Hipolito Point, Pacific coast of Baja California Sur, Mexico; Fusinus laticlavius sp. nov. from deep water off Danzante Island, western Gulf of California, Baja California Sur, Mexico; Fusinus seriatus sp. nov. from the Pacific coast of Baja California Sur, Mexico; Fusinus euekes sp. nov. from the eastern Gulf of California, Mexico; Araiofusus araios sp. nov. from deep water in Monterey Bay to the Gorda Bank off Cabo San Luca, Mexico; Araiofusus eueides sp. nov. from Monterey Bay to Orange County and Catalina Island, south to Cedros Island, Pacific Baja California, Mexico; Harfordia chucksnelli sp. nov. from the Channel Islands and off Santa Barbara; Harfordia mcleani sp. nov. from Monterey County throughout the Channel Islands and south to Cedros Island and Barbarofusus guadalupensis sp. nov. from Guadalupe Island, Pacific Baja California, Mexico.

A new name, Hesperaptyxis meridionalis, is proposed to replace the homonymous name Latirus melvilli Dall and Ochsner 1928 non Schepman, 1911, a Pliocene species from the Galapagos Islands. A lectotype is selected for the Recent species Fusus luteopictus Dall, 1877, and a neotype for the Pleistocene species Fusus barbarensis Trask 1855, the type species of Barbarofusus. Types of the previously-named species here assigned to Araiofusus, Harfordia and Barbarofusus are illustrated. Four new combinations are introduced: Araiofusus colpoicus (Dall, 1915), Harfordia arnoldi (Cossmann, 1903), H. robusta (Trask, 1855) and Barbarofusus kobelti (Dall, 1877).

Most of the smaller fusinine species from this area not dealt with here were assigned to the genus Hesperaptyxis in a previous paper (Snyder and Vermeij, 2016).