Melon fruit flies are economically important pests of cucurbit vegetables. The development and survival of melon fly was compared at six constant temperatures ranging from 16 to 36 °C and two carbon dioxide levels (380 and 570 ppm) under laboratory conditions. Temperature below 20 °C and above 32 °C proved less favourable for growth and development of melon fruit fly. It exhibited normal growth and development at 24 °C. Temperatures above 24 °C caused mortality of 19.07 % and up to 100 % at 36 °C. But, levels of elevated carbon dioxide did not elicit varied response to growth and development in four generations studied and confirmed.