Two new species of Xanthochorus Fischer 1884 (X. disalvoi sp. nov. and X. mogolloni sp. nov.) and two new species of Urosalpinx Stimpson 1865 (U. devriesi sp. nov. and U. lancellottii sp. nov.) are described from central Chile. Xanthochorus disalvoi sp. nov. is compared with X. cassidiformis (Blainville, 1832) and X. buxeus (Broderip, 1833). It differs from X. cassidiformis in having a comparatively smaller and narrower shell, a longer siphonal canal, a narrower aperture and narrower axial ribs, while broader or even absent in X. cassidiformis. It differs from X. buxeus in having a lower spire, a broader, less elongate shell with a lower spire, a comparatively longer siphonal canal a narrower aperture and a different spiral sculpture morphology. Xanthochorus mogolloni sp. nov. is also compared with X. buxeus, it differs mainly in having narrower primary and secondary cords, a longer siphonal canal and a lower spire. Urosalpinx devriesi sp. nov. is compared with Urosalpinx cala (Pilsbry, 1897). Urosalpinx devriesi differs in having a lower spire, a longer siphonal canal and a different spiral sculpture morphology. Urosalpinx lancellottii sp. nov. is compared with U. subangulata (Stearns, 1873); it differs in protoconch, axial ribs and spiral sculpture morphology. It differs from Vokesinotus perrugatus (Conrad, 1846) in having an obviously more fragile and smaller shell, and also in having different spiral sculpture morphology. The radulae of Xanthochorus cassidiformis and X. buxeus are illustrated.