Translator Disclaimer
1 March 2006 Campylobacter jejuni Strains of Human and Chicken Origin Are Invasive in Chickens After Oral Challenge
Katrine Nørrelund Knudsen, Dang Duong Bang, Lars Ole Andresen, Mogens Madsen
Author Affiliations +
Abstract

The aim of the study was to evaluate the colonizing ability and the invasive capacity of selected Campylobacter jejuni strains of importance for the epidemiology of C. jejuni in Danish broiler chickens. Four C. jejuni strains were selected for experimental colonization studies in day-old and 14-day-old chickens hatched from specific pathogen free (SPF) eggs. Of the four C. jejuni strains tested, three were Penner heat-stable serotype 2, flaA type 1/1, the most common type found among broilers and human cases in Denmark. The fourth strain was Penner heat-stable serotype 19, which has been shown to be associated with the Guillain Barré Syndrome (GBS) in humans. The minimum dose for establishing colonization in the day-old chickens was approximately 2 cfu, whereas two- to threefold higher doses were required for establishing colonization in the 14-day-old chickens. Two of the C. jejuni strains were shown to be invasive in orally challenged chickens as well as in three different human epithelial cell lines.

Katrine Nørrelund Knudsen, Dang Duong Bang, Lars Ole Andresen, and Mogens Madsen "Campylobacter jejuni Strains of Human and Chicken Origin Are Invasive in Chickens After Oral Challenge," Avian Diseases 50(1), 10-14, (1 March 2006). https://doi.org/10.1637/7376-051005R.1
Received: 10 May 2005; Accepted: 1 September 2005; Published: 1 March 2006
JOURNAL ARTICLE
5 PAGES


Share
SHARE
KEYWORDS
Campylobacter jejuni
colonization
oral challenge
organ invasion
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top