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1 June 2008 Sequence Analysis of the VP2 Hypervariable Region of Eight Very Virulent Infectious Bursal Disease Virus Isolates from the Northeast of China
Yanqing Yuwen, Yulong Gao, Honglei Gao, Xiaole Qi, Tieqiang Li, Wei Liu, Xiaomei Wang
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Abstract

Nucleotide sequences of the VP2 gene of eight infectious bursal disease viruses isolated from vaccinated chicken flocks in the northeast of China were determined. The sequence analysis showed that all of the isolates were also characterized by the vvIBDV conserved amino acid residues: 222A, 256I, 294I, and 299S. Four of them had one amino acid change (D→N) at position 212 in VP2 major hydrophilic peak A, while two of the four isolates had another one (A→V) at position 321 in major hydrophilic peak B. The other isolates were similar to the UK661 strain. Our findings demonstrated that the vvIBDV strains in the northeast of China could be diverse.

Yanqing Yuwen, Yulong Gao, Honglei Gao, Xiaole Qi, Tieqiang Li, Wei Liu, and Xiaomei Wang "Sequence Analysis of the VP2 Hypervariable Region of Eight Very Virulent Infectious Bursal Disease Virus Isolates from the Northeast of China," Avian Diseases 52(2), 284-290, (1 June 2008). https://doi.org/10.1637/8175-111707-Reg.1
Received: 28 November 2007; Accepted: 1 February 2008; Published: 1 June 2008
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KEYWORDS
northeast of China
sequence analysis
very virulent infectious bursal disease virus
VP2 hypervariable region
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