The ability of sperm to fertilize the egg is primarily dependent on sperm motility and membrane integrity. Nitric oxide (NO) plays a decisive role in regulating multiple functions within the male reproductive system. The aim of the present study is to determine the mechanism by which l-arginine confers a protective action on spermatozoa obtained from the goat epididymis. NO is synthesized from l-arginine by the enzyme nitric oxide-synthase (NOS) present in spermatozoa. A possible participation of NO and NOS in arginine action has been suggested.
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1 May 2006
Mechanism of Action of l-arginine on the Vitality of Spermatozoa is Primarily Through Increased Biosynthesis of Nitric Oxide
Sudha Srivastava,
Prashant Desai,
Evans Coutinho,
Girjesh Govil
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Nitric oxide
sperm
sperm capacitation
sperm maturation
sperm motility and transport