Skin and soft tissue infections (SSTIs) and methicillin-resistant Staphylococcus aureus (MRSA) are becoming increasingly prevalent in the healthcare field. Certain traditional medicines have been shown to have antibacterial properties. This study aims to identify medicinal plants with antibacterial properties against SSTI-associated bacteria and MRSA, and identify the specific antibacterial compounds within each extract. Five plant extracts were examined: burdock (Arctium minus), mullein (Verbascum thapsus), red clover (Trifolium pretense), yarrow (Achillea millefolium), and bilberry (Vaccinium myrtillas). The extracts were examined for antibacterial effects against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Enterococcus faecalis, Streptococcus pneumoniae, Enterococcus saccharolyticus, and MRSA. Mullein and red clover extracts were the most effective, inhibiting five of seven bacteria, including MRSA. Growth of the highly resistant bacterium was inhibited by mullein extract and red clover extract. The compounds identified by gas chromatography-mass spectrometry (GC-MS) within red clover and mullein with antibacterial properties were ethyl linolenate and ethyl-α-d-glucopyranoside, respectively. This is the first initial screening study to identify mullein and red clover extract as potential topical antibacterial agents against MRSA, which suggests that further study is needed.
You have requested a machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Neither BioOne nor the owners and publishers of the content make, and they explicitly disclaim, any express or implied representations or warranties of any kind, including, without limitation, representations and warranties as to the functionality of the translation feature or the accuracy or completeness of the translations.
Translations are not retained in our system. Your use of this feature and the translations is subject to all use restrictions contained in the Terms and Conditions of Use of the BioOne website.
Vol. 91 • No. 1