Fatty liver hemorrhagic syndrome (FLHS) is a metabolic disease mostly observed in laying hens that causes an economic toll on the poultry industry. To investigate the improving effects of biotin on FLHS in laying hens, a total of 135 Hy-Line Brown layers of 300-d-old were randomly divided into three groups and treated for 60 d. The hens from these three groups were fed with different diets: control group (the basal diet), pathology group [high-energy-low-protein diet (HELP)], and treatment group (HELP containing a biotin dosage of 0.3 mg kg-1). The results showed that the mRNA expression level of apolipoprotein A I (apoA I) in pathology group significantly (P < 0.01) decreased on day 60 compared with the control group, while the mRNA level of apolipoprotein B100 (apoB100) increased significantly in pathology group on day 30, whereas it decreased significantly on day 60 (P < 0.05). Significantly increased mRNA levels of apoA I and apoB100 were observed in treatment group compared with the pathology group on days 30 and 60 (P < 0.05 or P < 0.01). These results indicated that biotin could effectively alleviate the pathological changes and abnormal expression of apoA I and apoB100 induced by FLHS, which might closely relate to the ability of biotin to promote egg production.
How to translate text using browser tools
13 February 2020
The improving effects of biotin on hepatic histopathology and related apolipoprotein mRNA expression in laying hens with fatty liver hemorrhagic syndrome
Jiamei Huang,
Guyue Li,
Hongfeng Cao,
Fei Yang,
Chenghong Xing,
Yu Zhuang,
Caiying Zhang,
Ping Liu,
Huabin Cao,
Guoliang Hu
ACCESS THE FULL ARTICLE
It is not available for individual sale.
This article is only available to subscribers.
It is not available for individual sale.
It is not available for individual sale.
apolipoprotein A I
apolipoprotein B100
biotin
fatty liver hemorrhagic syndrome
laying hens