Preharvest fruit drop (PFD) of apple (Malus domestica Borkh.) can cause significant losses resulting in up to 50% reduction in yield in some years. In a 2-yr study, ‘Honeycrisp’ trees were treated with six foliar treatments including 20 mg·L^-1 1-naphthaleneacetic acid (NAA) 2 wk before anticipated harvest (WBAH), 125 mg·L^-1 aminoethoxyvinylglycine hydrochloride (AVG) 4 WBAH, AVG plus NAA 2 WBAH, and repeat sprays of 200 mg·L^-1 B, and 2000 mg·L^-1 Mg applied 48–93 d after full bloom to evaluate their effect on PFD and fruit quality. Fruit drop associated with broken pedicels and physiological causes was monitored. During a year with ∼43% PFD on untreated control trees, AVG retained up to ∼35% and NAA retained up to ∼27% of the total fruit number, relative to the control trees. The combination of AVG plus NAA had similar PFD compared with AVG alone, while B and Mg were similar to the control. The proportion of PFD associated with broken pedicels was ∼5%. Aminoethoxyvinylglycine delayed starch degradation, ethylene evolution, and blush skin colour development of fruit. This study supports the use of AVG 4 WBAH and NAA 2 WBAH to manage ‘Honeycrisp’ PFD, which may offer economic advantages for growing quality apples. Foliar sprays of Mg or B failed to reduce PFD.