Hematological Parameters, Plasma Polypeptide Profiles, and Human Anti-Cancer Bioactivity of Testudo graeca and Testudo horsfieldii Plasma

Elie K. Barbour; Nagy S. Abou Chakra; Lina Jaber; Pia A. Nehme; Houssam Shaib; Nada Usayran; Riyad Sadek; Hala Gali-Muhtasib

doi:10.2744/CCB-0652.1

1 August 2008 Hematological Parameters, Plasma Polypeptide Profiles, and Human Anti-Cancer Bioactivity of Testudo graeca and Testudo horsfieldii Plasma

Elie K. Barbour, Nagy S. Abou Chakra, Lina Jaber, Pia A. Nehme, Houssam Shaib, Nada Usayran, Riyad Sadek, Hala Gali-Muhtasib

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Chelonian Conservation and Biology, 7(1):141-145 (2008). https://doi.org/10.2744/CCB-0652.1

Abstract

We documented differential blood cell counts and plasma polypeptide profiles in Testudo graeca and T. horsfieldii raised in captivity in Lebanon, and investigated bioactivity of T. graeca plasma against a human colon cancer cell line (HCT-116). The percentage of red blood cells, thrombocytes, heterophils, basophils, lymphocytes, monocytes, and eosinophils did not differ significantly between the species during winter or spring. The total number of plasma polypeptides differed between the species, with 2 additional polypeptide bands in T. horsfieldii. Plasma from T. graeca significantly affected the percentage proliferation and percentage viability of human cancer cell line HCT-116.

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Elie K. Barbour, Nagy S. Abou Chakra, Lina Jaber, Pia A. Nehme, Houssam Shaib, Nada Usayran, Riyad Sadek, and Hala Gali-Muhtasib "Hematological Parameters, Plasma Polypeptide Profiles, and Human Anti-Cancer Bioactivity of Testudo graeca and Testudo horsfieldii Plasma," Chelonian Conservation and Biology 7(1), 141-145, (1 August 2008). https://doi.org/10.2744/CCB-0652.1

Received: 7 February 2006; Accepted: 1 March 2008; Published: 1 August 2008

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