A new terrestrial species of Colura (Dumort.) Dumort., from high elevations in the northern tropical Andes is described. The species differs from other members of the genus in the section Oidocorys Jovet-Ast ex Grolle on its unique oversized lobule and reduced lobe, and the smooth surface of the leaf cells. An identification key is provided for northern South America. Colura stotleri sp. nov., described here, is found at a single mountain top at 4700 m a.s.l. on peaty soil, with a lack of suitable habitats at higher elevations highlighting the threats posed by climate change on the conservation of mountain flora.