Forty-one new species and one new forma from regions north and west of Brazil are described and illustrated in miscellaneous genera of the Pleurothallidinae. The genera follow logical taxonomic delimitations. In alphabetical order, the new species and forma proposed herein are: Acianthera biseta, A. bryonii, A.carcinopsis, A. dubbeldamii, A. ericae; Acronia thoerleae; Alaticaulia apoloae, A. jimenezii; Brachionidium demissum; Crocodeilanthe vasquezii; Dracula soennemarkii, D. tobarii, D. vierlingii; Lepanthes biruviensis, L. calocerca, L. cercopetala, L. dactylopetala, L. gonzalezii, L. larsenii, L. nautica, L. nephridia, L. oblivia, L.pachychila, L. scoliosa, L. uncinata, L.yamileana; Lindleyalis saueri; Masdevallia deburghgraevei, M. dickinsoniana, M. ecallosa, M. rosacea, M. wetzelii; Porroglossum zelenkoi; Restrepia aristulifera forma leathersii; Scaphosepalum ximenae; Spilotantha aureoportensis; Stelis aguirreae, S. caesariata, S. ebenea, S. marioi, S. perexigua; and Trichosalpinx carmeniae. New combinations in the genus Acianthera are proposed: A. martinezii, A. quadricristata, A. venulosa, and A. zumbae. A new combination in Crocodeilanthe is proposed, C. erectiflora, as well as a new combination in Elongatia, E.jimii. Three species are proposed as synonyms: Crocodeilanthe franciscensis as a synonym of Pleurothallis divaricans; Dracula gerhardii as a synonym of D. diabola; and Lindleyalis hemirhoda as a synonym of the new combination L. nuda.