We describe a new species of Physalaemus from central Brazil. It is characterized by the following combination of traits: medium-sized; snout subelliptical in dorsal view, varying between rounded and protruding in lateral view; head longer than wide; snout long; dorsolateral fold present; small inguinal gland associated with dark ocellus present; tarsal tubercle present; poorly developed tarsal fold present and supernumerary tubercles on feet absent. The advertisement call is a single note with eight harmonics lasting 0.7–1.0 s in duration and emitted at intervals of 0.6–5.8 s. The dominant frequency varies from 1.9 to 3.1 kHz. The occurrence of the new species is in open habitats (disturbed or preserved) in central Brazil.