Laboratory trials were conducted on crape myrtle aphid Tinocallis kahawaluokalani (Kirkaldy) to assess the effectiveness and mode of action of one experimental Chenopodium-based botanical (QRD 400 Chenopodium ambrosioides var. ambrosioides) and retail insecticide products for the control of this insect pest and the effect of these products on different life stages of the multicolored Asian lady beetle Harmonia axyridis Pallas. For monitoring aphid densities, two sampling techniques were compared: 1) aphids per 2-cm diameter circular leaf sampling area; and 2) aphid-infested leaves per 5-leaf sample. In both techniques, pre- and post-treatment counts were conducted. Data obtained from both pre- and post-treatment analysis were pooled to provide an average number including analysis of variance with the means separated using Tukey's Honest Significant Difference, at P ≤ 0.05 level. A linear regression, with 95% mean prediction interval was performed on data assessing various treatment rates of QRD 400.