A geriatric male great horned owl (Bubo virginianus) that was a resident at a raptor center was presented for examination because of stridor and weight loss. Results of physical examination, diagnostic imaging, and biopsy were consistent with disseminated lymphoma involving the oropharynx, neck region (including thyroid and parathyroid glands), keel, spleen, and liver. Attempts to treat the owl with chlorambucil failed, and the owl was euthanatized 5 months later. Neoplastic cells from this owl were immunoreactive to CD-3 antibody, suggesting the lymphoma was of T-cell origin.
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1 September 2008
Disseminated Lymphoma of Presumptive T-cell Origin in a Great Horned Owl (Bubo virginianus)
Shachar Malka,
Torrie Crabbs,
Elizabeth B. Mitchell,
Ashley Zehnder,
Michael S. Kent,
Linda J. Lowenstine,
Michelle G. Hawkins
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Journal of Avian Medicine and Surgery
Vol. 22 • No. 3
September 2008
Vol. 22 • No. 3
September 2008
Avian
Bubo virginianus
CD-3
computed tomography
Endoscopy
great horned owl
immunohistochemistry