An adult, male double yellow-headed Amazon parrot (Amazona ochrocephala oratrix) was diagnosed with chronic lymphocytic leukemia based on results of a complete blood cell count and cytologic examination of a bone marrow aspirate. Treatment with oral chlorambucil was attempted, but no response was evident after 40 days. The bird was euthanatized, and the diagnosis of chronic lymphocytic leukemia was confirmed on gross and microscopic examination of tissues. Neoplastic lymphocytes were found in the bone marrow, liver, kidney, testes, and blood vessels. Based on CD3-positive immunocytochemical and immunohistochemical immunophenotyping, the chronic lymphocytic leukemia was determined to be of T-cell origin.
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1 December 2011
T-Cell Chronic Lymphocytic Leukemia in a Double Yellow-headed Amazon Parrot (Amazona ochrocephala oratrix)
Anna Osofsky,
Michelle G. Hawkins,
Oded Foreman,
Michael S. Kent,
William Vernau,
Linda J. Lowenstine
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Amazon parrot
Amazona ochrocephala oratrix
Avian
chemotherapy
chlorambucil
chronic lymphocytic leukemia
T-cell