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1 December 2000 Selection and Reversion of Azamethiphos-Resistance in a Field Population of the Housefly Musca domestica (Diptera: Muscidae), and the Underlying Biochemical Mechanisms
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Abstract

The organophosphorus insecticide, azamethiphos, is widely usedthroughout the world to control the housefly, Muscadomestica (L.). Since its commercial introduction to Denmark in1983 for this purpose, we have monitored the toxicity of azamethiphosto housefly populations at livestock farms throughout the country andcarried out regular field studies. The findings of our field studies,which have revealed a strong potential for resistance development, havebeen born out by regular surveys showing that resistance has increasedin recent years. Through the analysis of a field derived laboratorystrain, we have implicated oxidative and hydrolytic mechanisms togetherwith altered acetylcholinesterase in this resistance. Our field andlaboratory studies have also indicated that resistance is relativelyunstable, and can revert in the absence of selection. The implicationsof our findings for the continued efficacy of azamethiphos arediscussed.

Michael Kristensen, Mette Knorr, Andrew G. Spencer, and Jørgen B. Jespersen "Selection and Reversion of Azamethiphos-Resistance in a Field Population of the Housefly Musca domestica (Diptera: Muscidae), and the Underlying Biochemical Mechanisms," Journal of Economic Entomology 93(6), 1788-1795, (1 December 2000). https://doi.org/10.1603/0022-0493-93.6.1788
Received: 3 November 1999; Accepted: 1 August 2000; Published: 1 December 2000
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