Laboratory studies were conducted to determine the effects of vacuum and controlled atmosphere on mortality of aphids, Nasonovia ribisnigri (Mosley) and Macrosiphum euphorbiae (Thomas), and leafminer, Liriomyza langei Frick, and on the visual quality of iceberg lettuce at three different temperatures. Vacuum at 50 mbar and controlled atmosphere with 6% CO₂ were effective in controlling aphids and leafminer larvae. Complete control of N. ribisnigri and M. euphorbiae was achieved with vacuum treatments and 6% CO₂ CA treatments at 5°C in 4 d. Mortality was >96% when leafminer larvae were treated with vacuum and 6% CO₂ CA treatments for 4 d. However, leafminer pupae were more tolerant to the treatments and highest mortality was close to 60% in 4 d with CO₂ under vacuum. None of the treatments had negative effects on visual quality of iceberg lettuce. Results from this study are encouraging and warrant further and large-scale research.