Translator Disclaimer
30 December 2021 Cytologic and Histologic Findings of Nephroblastoma in a Captive Desert Tortoise (Gopherus agassizii)
Elise E. B. LaDouceur, Michael M. Garner, Ginger F. Hammett, Louisa M. Asseo
Author Affiliations +
Abstract

A 97-yr-old, male, captive desert tortoise (Gopherus agassizii) had a 2-month history of lethargy. Imaging with ultrasound, radiographs, and computed tomography revealed a 10-cm-diameter mass in the caudal coelom. Fine-needle aspiration revealed spindle and epithelial cell proliferations with formation of rosettes. Exploratory surgery was performed and the mass was removed and submitted for pathology. There was no evidence of metastasis on imaging or at surgery. Histology revealed a mass arising from and compressing the kidney. The mass was composed of primitive glomeruli, tubules, blastemal cells, and mesenchymal cells, features that are diagnostic for nephroblastoma. Tubules were reactive to cytokeratin and mesenchymal cells were reactive to desmin via immunohistochemistry; other immunohistochemical markers were either negative (e.g., S-100) or noncontributory (e.g., epithelial membrane antigen, myogenin, vimentin, and Wilms' Tumor 1). This is the first report of nephroblastoma in a chelonian.

Elise E. B. LaDouceur, Michael M. Garner, Ginger F. Hammett, and Louisa M. Asseo "Cytologic and Histologic Findings of Nephroblastoma in a Captive Desert Tortoise (Gopherus agassizii)," Journal of Herpetological Medicine and Surgery 31(4), 278-282, (30 December 2021). https://doi.org/10.5818/JHMS-D-21-00002
Published: 30 December 2021
JOURNAL ARTICLE
5 PAGES


Share
SHARE
KEYWORDS
desert tortoise
Gopherus agassizii
immunohistochemistry
neoplasia
nephroblastoma
Wilms' Tumor
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top