The aim of this study is to investigate whether a natural cycle intrauterine insemination (NC-IUI) monitored with ultrasonography and serum estradiol level can improve the pregnancy rate (PR) of NC-IUI. A total of 311 cycles of 135 cases was treated with a NC-IUI using a ultrasonographic monitor for follicular development (Group A). And a total of 308 cycles of 131 cases underwent a NC-IUI monitored baseline ovarian cysts, follicular development and ovulation using ultrasonography and serum estradiol level (Group B). Forty-two cycles (12.0%) were cancelled due to baseline ovarian cysts and 20 cycles (6.1%) were excluded from group B because of a luteinized unruptured follicle. In group A and B, 16 pregnancies (5.1% per cycle) and 32 pregnancies (10.4% per cycle) were obtained respectively. The differences between the PRs of the two groups attained statistical significance (P < 0.05). Our data indicated that a NC-IUI monitored with ultrasonography and serum estradiol level may improve the PR of NC-IUI.
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1 April 2007
Investigation of Whether a Follicular Assessment using Ultrasonography and Serum Estradiol Measurements Can Improve the Pregnancy Rate of a Natural Menstrual Cycle Intrauterine Insemination
Naoki Yamashita,
Yuji Fujino,
Ayako Yokoyama,
Mayumi Honda,
Sachiko Miyata,
Miki Mori,
Yuka Sekiguchi,
Megumi Hoki
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Journal of Mammalian Ova Research
Vol. 24 • No. 2
April 2007
Vol. 24 • No. 2
April 2007
Follicular assessment
Intrauterine insemination
Natural menstrual cycle
Serum estradiol level
Ultrasonography