The association of microhabitat variables and capture (= occurrence) of striped skunks (Mephitis mephitis) was assessed at 3 sites in western Tennessee. Sixteen features were included in univariate and stepwise logistic regressions to investigate relationships between occurrence and habitat factors and to construct models predictive of occurrence. Accuracy of models was examined using jackknife procedures, and maps predictive of occurrence were developed through semivariance and kriging analyses. Average height of stand, hardwood snags >35 cm diameter at breast height, number of stems, distance to permanent water sources, and distance to open areas were among the habitat features most frequently found to be related to occurrence. Models derived from logistic regression predicted occurrence of the species at varying levels (56% to 75%). Overall, classification percentages appeared to be at a level useful for predicting the occurrence of M. mephitis, and mapping procedures sufficient for illustrating the association between occurrence and habitat.