Repellent efficacy of N,N-diethyl-3-methyl-benzamide (deet), the piperidine, 1-[3-cyclohexen-1-ylcarbonyl]-2-methylpiperidine (AI3-37220), and a 1:1 ratio of deet AI3-37220 were evaluated topically (0.25 mg/cm2 applied in ethanol solution) on human volunteers against the mosquito Aedes communis (DeGeer) and the black fly Simulium venustum Say. The average repellency of all three formulations was >95% at 4 h. For both mosquitoes and black flies, deet alone provided <90% protection at 6 h, whereas AI3-37220 provided >95% protection. Although repellent treatments were not significantly different overall, the contrasts between AI3-3720 versus deet were significant at 6 and 8 h. The 95% confidence interval on percent repellency at 6 h ranged from 90.1 to 98.9% for AI3-37220 versus 64.3 to 82.2% for deet, and at 8 h ranged 76.1 to 88.5% for AI3-37220 versus 47.8 to 64.0% for deet. Similarly, the confidence interval for protection against black flies at 6 h by (AI3-37220 ranged from 86.3 to 99.5% and did not overlap with the confidence interval provided by deet alone (51.2 to 78.8%). There was no evidence of synergistic repellency from a combination of the two compounds; i.e., protection from combined compounds was no better than either repellent used alone.
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1 November 2000
Field Evaluation of Deet and a Piperidine Repellent Against Aedes communis (Diptera: Culicidae) and Simulium venustum (Diptera: Simuliidae) in the Adirondack Mountains of New York
Mustapha Debboun,
Daniel Strickman,
Victoria B. Solberg,
Richard C. Wilkerson,
Kenneth R. McPherson,
Claudia Golenda,
Lisa Keep,
Robert A. Wirtz,
Robert Burge,
Terry A. Klein
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Journal of Medical Entomology
Vol. 37 • No. 6
November 2000
Vol. 37 • No. 6
November 2000
Aedes communis
AI3-37220
DEET
piperidine
repellents
Simulium venustum
