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21 July 2023 Methanol and acetone extracts from the leaves of selected aromatic plants affect survival of field collected Anopheles arabiensis (Diptera: Culicidae) from Kisumu, Kenya
Dimitri Wendgida Wangrawa, Félix Yaméogo, Aboubacar Sombié, Edward Esalimba, Eric Ochomo, Dov Borovsky, Athanase Badolo, Antoine Sanon
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Abstract

The massive and inappropriate use of synthetic insecticides is causing significant and increasing environmental disruption.Therefore, developing effective natural mosquitocidal compounds could be an alternative tool for malarial vector control.The present study investigates the larvicidal and adulticidal effect of methanol and acetone extracts of leaves from Lippia chevalieri, Lippia multiflora, Cymbopogon schoenanthus, and Lantana camara against Anopheles arabiensis, to control the most widespread vector transmitting malaria in sub-Saharan. Africa. Extracts were evaluated following WHO modified test procedure against third- to fourth-instar larvae and, non-blood-fed females from 3- to 5-day-old field populations of An. arabiensis under laboratory conditions usingWHO larval and CDC bottle bioassays, respectively. Mortality was recorded after 24-h exposure and several compounds were identified in the extracts. The methanolic and acetonic extracts of L. camara were effective against larvae showing lethal concentrations to 50% (LC50) of the population, at 89.48 and 58.72 ppm, respectively.The acetonic extracts of C. schoenanthus and L. chevalieri showed higher toxicities LC50s of 0.16% and 0.22% against female adults, respectively. The methanolic extracts of L. multiflora and L. chevalieri LC50s were effective at 0.17% and 0.27%, respectively, against female adults.These results indicate that the plant extracts tested may represent effective means to control An. arabiensis when used to treat the surface of the marshes.

Dimitri Wendgida Wangrawa, Félix Yaméogo, Aboubacar Sombié, Edward Esalimba, Eric Ochomo, Dov Borovsky, Athanase Badolo, and Antoine Sanon "Methanol and acetone extracts from the leaves of selected aromatic plants affect survival of field collected Anopheles arabiensis (Diptera: Culicidae) from Kisumu, Kenya," Journal of Medical Entomology 60(5), 1030-1037, (21 July 2023). https://doi.org/10.1093/jme/tjad066
Received: 21 March 2023; Accepted: 19 June 2023; Published: 21 July 2023
JOURNAL ARTICLE
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KEYWORDS
adulticidal
Anopheles arabiensis
compound
larvicidal
plant extract
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