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1 January 1988 COMPARISON OF SERUM AND LUNG EXTRACTS FOR SURVEYS OF WILD ANIMALS FOR ANTIBODIES TO FRANCISELLA TULARENSIS BIOVAR PALAEARCTICA
Torsten Mörner, Gunnar Sandström, Roland Mattsson
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Abstract

A comparative study of the antibody titer against Francisella tularensis biovar palaearctica in serum and lung extract was made using different immunoassays. Samples were taken from experimentally-infected goshawks (Accipiter gentilis) and European beavers (Castor fiber), and in a held survey of wild beavers. Good accordance between the antibody titer in serum and in lung extract was found in the experimental studies. However, the antibody titer was generally one- to three-fold lower in lung extract than was the titer of serum. Results in the field survey were less reliable. Estimating antibody titer in lung extract is a practical method for surveys for antibody levels, and an alternative to serological surveys, despite lower sensitivity as compared to serum.

Mörner, Sandström, and Mattsson: COMPARISON OF SERUM AND LUNG EXTRACTS FOR SURVEYS OF WILD ANIMALS FOR ANTIBODIES TO FRANCISELLA TULARENSIS BIOVAR PALAEARCTICA
Torsten Mörner, Gunnar Sandström, and Roland Mattsson "COMPARISON OF SERUM AND LUNG EXTRACTS FOR SURVEYS OF WILD ANIMALS FOR ANTIBODIES TO FRANCISELLA TULARENSIS BIOVAR PALAEARCTICA," Journal of Wildlife Diseases 24(1), 10-14, (1 January 1988). https://doi.org/10.7589/0090-3558-24.1.10
Received: 3 February 1987; Published: 1 January 1988
KEYWORDS
Accipiter gentilis
antibodies
beaver
Castor fiber
ELISA
Francisella tularensis
goshawk
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