A total of 15 immobilizations were performed on 12 common genets (Genetta genetta) with a combination of ketamine hydrochloride (KE) and xylazine hydrochloride (XY). Ten immobilizations were successful using a single mean administration of 5.7 mg/kg (SD = 1.7) KE and 9.8 mg/kg (SD = 2.9) XY; five immobilizations required supplemental doses that averaged 3.4 mg/kg KE and 1.9 mg/kg XY. Initial doses of 7 mg/kg KE and 10 mg/kg XY are recomended to successfully immobilize genets. Mean induction time and arousal time were 8 min (SD = 4, n = 10) and 113 min (SD = 57, n = 9), respectively. A combination of KE and XY appears to be an effective and safe immobilizing agent for common genets.