Efficacy of SAD (Berne) Rabies Vaccine Given by the Oral Route in Two Species of Jackal (Canis mesomelas and Canis adustus)

J. Bingham; A. Kappeler; F. W. G. Hill; A. A. King; B. D. Perry; C. M. Foggin

doi:10.7589/0090-3558-31.3.416

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1 July 1995 Efficacy of SAD (Berne) Rabies Vaccine Given by the Oral Route in Two Species of Jackal (Canis mesomelas and Canis adustus)

J. Bingham, A. Kappeler, F. W. G. Hill, A. A. King, B. D. Perry, C. M. Foggin

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J. of Wildlife Diseases, 31(3):416-419 (1995). https://doi.org/10.7589/0090-3558-31.3.416

Abstract

Eight black-backed jackals (Canis mesomelas) and seven side-striped jackals (Canis adustus) were given SAD (Berne) rabies vaccine by direct oral instillation. Three different vaccine doses were used: 10⁶³, 10⁶⁸ and 10⁷⁵ median tissue culture infectious doses. Two additional jackals were given vaccine in chicken heads. One group of jackals was challenged with a lethal dose of jackal-derived rabies virus 1 mo after vaccination and a second group 12 mo after vaccination. All 17 vaccinated jackals developed high and persistent serum neutralizing antibody titers. All challenged jackals resisted a lethal dose of rabies virus, whereas three control jackals given the same challenge succumbed to rabies.

Bingham, Kappeler, Hill, King, Perry, and Foggin: Efficacy of SAD (Berne) Rabies Vaccine Given by the Oral Route in Two Species of Jackal (Canis mesomelas and Canis adustus)

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J. Bingham, A. Kappeler, F. W. G. Hill, A. A. King, B. D. Perry, and C. M. Foggin "Efficacy of SAD (Berne) Rabies Vaccine Given by the Oral Route in Two Species of Jackal (Canis mesomelas and Canis adustus)," Journal of Wildlife Diseases 31(3), 416-419, (1 July 1995). https://doi.org/10.7589/0090-3558-31.3.416

Received: 18 May 1994; Published: 1 July 1995

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