An enzyme-linked immunosorbent assay (ELISA) and a serum neutralization (SN) test were developed to measure serum antibodies against the adenovirus causing hemorrhagic disease in free-ranging and captive experimentally-infected black-tailed deer (Odocoileus hemionus columbianus) in California (USA). There was a strong (rho = 0.874) and significant (P < 0.0001) correlation between ELISA and SN titers, although the SN assay was more sensitive than the ELISA.
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1 April 2000
Serologic Detection of Adenoviral Hemorrhagic Disease in Black-Tailed Deer in California
Jean-Martin Lapointe,
Leslie W. Woods,
Howard D. Lehmkuhl,
M. Kevin Keel,
Paul V. Rossitto,
Pamela K. Swift,
N. James MacLachlan
Journal of Wildlife Diseases
Vol. 36 • No. 2
April 2000
Vol. 36 • No. 2
April 2000
Adenovirus
black-tailed deer
enzyme-linked-immunosorbent assay–serum neutralization
Odocoileus hemionus columbianus
serology