Test Characteristics of Assays to Detect Mycobacterium bovis Infection in High-Prevalence African Buffalo (Syncerus caffer) Herds

Netanya Bernitz; Tanya J. Kerr; Candice de Waal; David V. Cooper; Robin M. Warren; Paul D. Van Helden; Sven D. C. Parsons; Michele A. Miller

doi:10.7589/2019-06-173

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Netanya Bernitz,¹ Tanya J. Kerr,¹ Candice de Waal,¹ David V. Cooper,² Robin M. Warren,¹ Paul D. Van Helden,¹ Sven D. C. Parsons,¹ Michele A. Miller^1,*

¹1Department of Science and Technology–National Research Foundation Centre of Excellence for Biomedic
²2Ezemvelo KwaZulu-Natal Wildlife, PO Box 25, Mtubatuba 3935, South Africa

^*Corresponding author (email: miller@sun.ac.za)

Abstract

A herd of African buffaloes (Syncerus caffer) was tested for Mycobacterium bovis infection using three cytokine release assays. All animals were subsequently euthanized and mycobacterial culture determined the infection prevalence (52%) and diagnostic characteristics. Sensitivities were lower than previously reported and results provide new insight into the practical utility of these assays.

Citation Download Citation

Netanya Bernitz, Tanya J. Kerr, Candice de Waal, David V. Cooper, Robin M. Warren, Paul D. Van Helden, Sven D. C. Parsons, and Michele A. Miller "Test Characteristics of Assays to Detect Mycobacterium bovis Infection in High-Prevalence African Buffalo (Syncerus caffer) Herds," Journal of Wildlife Diseases 56(2), 462-465, (31 March 2020). https://doi.org/10.7589/2019-06-173

Received: 27 June 2019; Accepted: 1 October 2019; Published: 31 March 2020

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