The liver fluke Fasciola gigantica was recovered from 58 percent of 82 African buffalo (Syncerus caffer), 47 percent of 103 Uganda kob (Adenota (Kobus) kob), and 47 percent of 47 Jackson's hartebeest (Alcelaphus buselaphus jacksoni) examined in the West Acholi District of Uganda in 1965–67. None of 22 oribi (Ourebia ourebi) was infected. There was no significant difference in prevalence between males and females or between host age groups except in Jackson's hartebeest. In this host the prevalence was higher in older animals.
In 5 percent of the infected hartebeest, 17 percent of the infected kob, and 69 percent of the infected buffalo, flukes were recovered only from the gall bladder. The importance of examining the gall bladder in addition to the bile ducts to detect F. gigantica is emphasized.