Two cases of fatal cryptococcosis are described, one of Cryptococcus neoformans infection in a Gilbert's potoroo (Potorous gilbertii) and one of Cryptococcus gattii infection in a long-nosed potoroo (Potorous tridactylus). The diagnoses were confirmed by culture and specific immunohistochemistry, respectively. The long-nosed potoroo tested positive using the latex cryptococcal antigen test (LCAT), whereas the Gilbert's potoroo had a negative LCAT result despite having advanced disease of some duration. In both cases, the clinical presentation was a progressive neurologic disease associated with a central nervous system infection. Pulmonary infection was also observed in the long-nosed potoroo. Specific treatment with antifungal agents was unsuccessful in the long-nosed potoroo.
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1 December 2007
CRYPTOCOCCOSIS IN GILBERT'S AND LONG-NOSED POTOROO
R. J. Vaughan,
S. D. Vitali,
P. A. Eden,
K. L. Payne,
K. S. Warren,
D. Forshaw,
J. A. Friend,
A. M. Horwitz,
C. Main,
M. B. Krockenberger,
R. Malik
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Journal of Zoo and Wildlife Medicine
Vol. 38 • No. 4
December 2007
Vol. 38 • No. 4
December 2007
Cryptococcus gattii
Cryptococcus neoformans
itraconazole
marsupial
Potoroo