Alternative Therapeutic Options for Medical Management of Epilepsy in Apes

Trevor Gerlach; Victoria L. Clyde; George L. Morris; Barbara Bell; Roberta S. Wallace

doi:10.1638/2010-0184.1

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1 June 2011 Alternative Therapeutic Options for Medical Management of Epilepsy in Apes

Trevor Gerlach, Victoria L. Clyde, George L. Morris, Barbara Bell, Roberta S. Wallace

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J. of Zoo and Wildlife Medicine, 42(2):291-294 (2011). https://doi.org/10.1638/2010-0184.1

Abstract

Phenobarbital has been the primary antiepileptic drug used in primates, but the dosage required for seizure control is frequently associated with significant side effects. Newer antiepileptic drugs and adjunctive therapies currently being used in human medicine provide additional options for treatment of nonhuman primates. This report describes different drug regimes used for control of epileptic seizures in apes at the Milwaukee County Zoo (Milwaukee, Wisconsin, USA), including the addition of acetazolamide to phenobarbital, levetiracetam, carbamazepine, and the use of extended cycle oral contraceptives to assist seizure control in female apes with catamenial epilepsy.

American Association of Zoo Veterinarians

Citation Download Citation

Trevor Gerlach, Victoria L. Clyde, George L. Morris, Barbara Bell, and Roberta S. Wallace "Alternative Therapeutic Options for Medical Management of Epilepsy in Apes," Journal of Zoo and Wildlife Medicine 42(2), 291-294, (1 June 2011). https://doi.org/10.1638/2010-0184.1

Received: 13 October 2010; Published: 1 June 2011

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