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1 December 2014 ACUTE LYMPHOBLASTIC LEUKEMIA IN A PYGMY HIPPOPOTAMUS (HEXAPROTODON LIBERIENSIS)
Paul McCurdy, Cheryl Sangster, Scott Lindsay, Larry Vogelnest
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Abstract

A captive, 31-yr-old, intact male pygmy hippopotamus presented with nonspecific signs of weight loss, inappetence, diarrhea, and lethargy. After 5 wk of diagnostic investigation and symptomatic treatment, an acute leukemic process with concurrent polycystic kidney disease was suspected. The animal's condition continued to deteriorate prompting euthanasia. Necropsy, histopathologic, and immunohistochemical examination confirmed acute T-cell lymphoblastic leukemia and polycystic kidneys. Acute T-cell lymphoblastic leukemia has not previously been documented in this species; however, polycystic kidney disease has been reported. This case report adds to the increasing number of pygmy hippopotamuses diagnosed with polycystic kidney disease and describes acute T-cell lymphoblastic leukemia, a previously unreported disease of this species.

Copyright 2014 by American Association of Zoo Veterinarians
Paul McCurdy, Cheryl Sangster, Scott Lindsay, and Larry Vogelnest "ACUTE LYMPHOBLASTIC LEUKEMIA IN A PYGMY HIPPOPOTAMUS (HEXAPROTODON LIBERIENSIS)," Journal of Zoo and Wildlife Medicine 45(4), 906-910, (1 December 2014). https://doi.org/10.1638/2014-0005.1
Received: 14 January 2014; Published: 1 December 2014
JOURNAL ARTICLE
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KEYWORDS
Hexaprotodon liberiensis
hippopotamus
leukemia
lymphoblastic
Polycystic kidney disease
PYGMY
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