Peromyscus perfulvus Osgood, 1945, is a medium-sized rodent with the English name of tawny deermouse. It is 1 of 56 species in the genus Peromyscus and has upperparts of bright cinnamon rufous along with creamy white underparts. This Mexican endemic is distributed from coastal lowlands of Jalisco and Colima to the interior of Michoacan, northernmost Guerrero, and the southwestern corner of the state of Mexico. The species is highly arboreal and inhabits tropical deciduous forest, semideciduous forest, and thorn scrub. Given its small geographic range coupled with microhabitat preferences and the fact that relevant habitats increasingly have been altered, P. perfulvus should be considered to be of conservation concern.