Seven new species of Faramea Aublet (Rubiaceae, Coussareae) are newly described from Colombia, Ecuador, Panama, and Peru. The new species F. colombiana C. M. Taylor from northwestern Colombia differs from F. robusta C. M. Taylor by its longer pedicels and larger flowers; F. condorica C. M. Taylor from southeastern Ecuador differs from F. phyllonomoides Standley by its longer calyx limbs and corollas with the tubes about twice as long as the lobes; F. frondosa C. M. Taylor from Panama differs from F. eurycarpa Donnell Smith by its oblanceolate to obovate calyx lobes 3.5–7 mm long; F. melicoccoides C. M. Taylor from western Colombia is distinguished by its relatively large fruits with a thickened pericarp, juicy mesocarp, and single smooth seed; F. ortiziana C. M. Taylor from Amazonian Peru differs from F. guianensis (Aublet) Bremekamp by its often terminal inflorescences and larger flowers and fruits; F. robusta C. M. Taylor from northwestern Colombia differs from F. polytriadophora Bremekamp by its longer peduncles and larger flowers; and F. schunkeana C. M. Taylor from central Peru differs from F. morilloi Steyermark by its leaves obtuse to rounded or cordulate at base, its larger corollas, and its smooth seeds.