Two new species of Lachemilla (Focke) Rydberg (Rosaceae) from the Andes of Ecuador and Colombia are described and illustrated. Lachemilla llanganatensis Romoleroux, from Ecuador, is characterized by its loosely ascending habit, sparsely short-hispid indumentum, presence of entire basal leaves, and ascending to spreading, verticillate stem leaves. The flowers are grouped in cymes of three to six flowers, with spreading sepals and episepals, and the hypanthia are often sparsely hirsute. Lachemilla kieftiana Romoleroux, from Colombia, is distinguished by its stoloniferous habit and basal leaves in rosettes with subreniform to 3-lobed, sericeous blades. The flowers are grouped in cymes of three to 10 flowers, subsessile, floral bracts free, with ascending sepals and episepals, and the hypanthia are mostly sericeous.