A revision of the Andean species of Ocotea Aubl. (Lauraceae) with hermaphrodite flowers and the lower leaf surface completely covered by the pubescence is presented. A key to the 22 recognized species is provided. Fourteen species are described as new: O. comata van der Werff, O. micrantha van der Werff, and O. stenophylla van der Werff from Bolivia; O. gentryi van der Werff, O. pedicellata van der Werff, and O. umbrina van der Werff from Colombia; O. loxensis van der Werff, O. palaciosii van der Werff, O. pautensis van der Werff from Ecuador; O. andina van der Werff, O. glabriflora van der Werff, O. pajonalis van der Werff, and O. trematifera van der Werff from Peru; and finally, the single species O. guaramacalensis van der Werff from Venezuela. Lectotypification is provided for the name O. jelskii Mez.