Three new species of Zanthoxylum L. (Rutaceae) from Andean Ecuador are here described based upon their morphological characters: Z. complexum Reynel, Z. kallunkiae Reynel, and Z. pluvimontanum Reynel & D. Tarazona. They all belong to the most speciose section of the genus, Macqueria Comm. ex Triana & Planch, and within it, they can be distinguished by several characters; each one belongs to a different species group of the mentioned section.
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