A new radiolarian genus, Ganjiangmoyea gen. nov., was discovered from the Lopingian (upper Permian) of the Yutouling section, Xiaodong area, Guangxi Zhuang Autonomous Region, South China. Ganjiangmoyea includes one new species (G. conica gen. et sp. nov.) and one possible new species (G.? striata gen. et sp. nov.). This new genus is characterized by numerous, swordlike radial spines extending from a central test. Single spines, presumably detached from the central test, co-occur with the Ganjiangmoyea species. Owing to these characteristics, Ganjiangmoyea could be placed under the family Oertlispongidae Kozur and Mostler. Paroertlispongus Kozur and Mostler and Pararchaeospongoprunum Lahm, belonging to the Oertlispongidae, also occur in the Permian, but their spines are bipolar and are not easily detached from the central test. Some of the Oertlispongidae genera, which occur abundantly in the Middle Triassic, also possess easily detached spines. Ganjiangmoyea might belong to a lineage of the Oertlispongidae that differs from that of Paroertlispongus and Pararchaeospongoprunum.