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1 November 2003 Pothomorphe umbellata Extract Prevents α-Tocopherol Depletion After UV-irradiation
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Abstract

In this work we evaluated the influence of topical application of P. umbellata root extract gel, containing 0.1% of 4-nerolidylcathecol, on the antioxidant network in UV-induced oxidative damage in hairless mouse skin. The UV-irradiation had no influence on ascorbic acid levels or on the antioxidant enzyme (superoxide dismutase, catalase, glutathione reductase and glutathione peroxidase) activities, but topical P. umbellata treatment protected α-tocopherol from being depleted after UV-irradiation. α-Tocopherol concentration decreased significantly (≈40%, P < 0.01) in the irradiated control groups, whereas in the P. umbellata–treated group, α-tocopherol was totally preserved (≈100%, P > 0.05). These data demonstrate that P. umbellata may be successfully used as a topical photoprotective agent.

Cristina D. Ropke, Renata R. Meirelles, Vanessa V. da Silva, Tânia C. H. Sawada, and Silvia B. M. Barros "Pothomorphe umbellata Extract Prevents α-Tocopherol Depletion After UV-irradiation," Photochemistry and Photobiology 78(5), 436-439, (1 November 2003). https://doi.org/10.1562/0031-8655(2003)078<0436:PUEPTD>2.0.CO;2
Received: 28 April 2003; Accepted: 1 August 2003; Published: 1 November 2003
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