Two species of Holcocera Clemens (Lepidoptera: Coleophoridae: Blastobasinae: Holcocerini) are known to feed on Persea americana Mill. (Lauraceae), but their frequency of infestation appears low. One species, Holcocera plagatola, n. sp., from Guatemala, is described herein. Holcocera iceryaeella (Riley) is known only from California and has been recorded on many different host plants; it is also known to be a predator of immature Hemiptera and scale insects. Photographs of the imagos of both Holcocera species are included, in addition to illustrations of the male and female genitalia. We comment on host preferences for both species.