The genus Dyrines, is revised for the first time since Simon provided the name in 1903 to replace the preoccupied Drances. A female lectotype is designated for the type species, Dyrines striatipes (Simon 1898), which is redescribed and illustrated. The holotype of D. taeniatus Mello-Leitão 1943 is a tiny spiderling and is considered a nomen dubium. Dyrines lineatipes Petrunkevitch 1925 is regarded as a junior synonym of D. striatipes. Dyrines rubriosignatus Mello-Leitão 1943 is transferred to the genus Thaumasia, resulting in Thaumasia rubrosignata (Mello-Leitão 1943b), new combination. Two new species are described and illustrated: D. huanuco from Huanuco, Peru, and D. ducke from Reserva Florestal Adolfo Ducke near Manaus, Brazil.