Dictyostelium discoideum is a useful model for molecular studies of cell biology and development. The 34-megabase Dictyostelium genome is currently being sequenced through the efforts of an international consortium. The genome is expected to encode 8–10,000 genes, including all those required for a free-living eukaryote capable of multicellular development. A complete description of the Dictyostelium genome will open the way toward the application of genome-based experimental approaches to studies of cell biology and development in this organism, and allow detailed physiological and evolutionary comparisons to other species.
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1 July 2000
Toward the Functional Analysis of the Dictyostelium discoideum Genome
Richard Sucgang,
G. A. D. Shaulsky,
Adam Kuspa
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The Journal of Eukaryotic Microbiology
Vol. 47 • No. 4
July 2000
Vol. 47 • No. 4
July 2000
cell motility
development
functional genomics
Genetics
genome sequencing
morphogenesis