Eight nests of the Giant Conebill (Oreomanes fraseri, Family Thraupidae) were found in Polylepis forest fragments in Cochabamba Department (Sacha Loma and Cuturi) of Bolivia during 2002–2004. The breeding period of the Giant Conebill extended from September to December at the beginning of the rainy season. The nests were open cups with an average outside width of 20 cm and a thick rim of 5.5 cm; the average clutch size was 1.86. Nests were constructed mostly with parts of Polylepis trees and a variety of mosses. All nests located were in the interior of forests, well camouflaged, and in trees with an average height of 3.16 m. Control of human disturbance, especially burning, is needed for protection of the habitat of the Giant Conebill.