Mesosulfuron is often applied to wheat at a time of year when top-dress nitrogen is also applied. Current labeling for mesosulfuron cautions against applying nitrogen within 14 d of herbicide application. Soft red winter wheat response to mesosulfuron and urea ammonium nitrate (UAN) applied sequentially and in mixtures was determined at three locations in North Carolina and Georgia during 2005 and 2006. Mesosulfuron at 0, 15, and 30 g ai/ha was applied in water to wheat at Feekes growth stage (GS) 3 followed by UAN at 280 L/ha 2 h, 7 d, 14 d, and 21 d after mesosulfuron. Mesosulfuron applied in UAN was also evaluated in 2006. Mesosulfuron injured wheat 6 to 9% in 2005 and 12 to 23% in 2006 when UAN was applied 2 h or 7 d after the herbicide. Wheat injury did not exceed 8% when UAN was applied 14 or 21 d after the herbicide. Greatest injury, 35 to 40%, was noted when mesosulfuron and UAN were combined. Wheat yield was unaffected by mesosulfuron or time of UAN application in 2005. In 2006, yield was affected by the timing of UAN application relative to mesosulfuron; wheat yield increased as the interval, in days, between UAN and herbicide applications increased. To avoid crop injury and possible yield reduction, mesosulfuron and UAN applications should be separated by at least 7 to 14 d. These findings are consistent with precautions on the mesosulfuron label.

Nomenclature: Mesosulfuron (proposed common name), 2-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-4-[[(methylsulfonyl)amino]methyl]benzoic acid; soft red winter wheat, Triticum aestivum L. ‘26R61’, ‘Coker 9184’, ‘SS 8308’.