There is an urgent need for brackish groundwater-based irrigation methods to be developed for saline soils that are effective, economically advantageous, and environmentally friendly. The use of both ionized brackish water and polyacrylamide (PAM) might provide such a method. The long-term use of brackish water irrigation can lead to the secondary salinization of soil and, as a consequence, restrict the development of the agricultural economy. Here, we conducted one-dimensional vertical infiltration experiments to examine the effects of ionized brackish water and PAM on soil infiltration characteristics. The result indicated that the water retention of soil first increased and then decreased with the increased in PAM application rates. The maximum water retention of soil was obtained in PAM application of 0.04% for ionized brackish water treatment. Soil water storage for the 0.04% PAM application under ionized brackish water irrigation was the highest and 5.1% higher compared with non-ionized brackish water at a PAM application rate of 0.04%. The ionized brackish water treatment at a PAM application rate of 0.04% improved the desalinization efficiency by 2.3% compared with non-ionized brackish water treatment. Thus, ionized treatment and PAM application are effective for improving the characteristics of soil water and salt transport and permit the safe use of brackish groundwater for irrigation.