A new species of Callirhytis Förster 1869 (Hymenoptera: Cynipidae: Cynipini) is described from Panama: Callirhytis cameroni sp. nov. Callirhytis cameroni is the first species of genus Callirhytis ‘sensu lato’ recorded from the Neotropical region. The new species induces galls on Quercus salicifolia Neé (Fagaceae, sect. Lobatae). The diagnostic characteristics, gall description, distribution and biological data of the new species are given.