A new genus in the Zygopetalinae is proposed based on morphological, ecological, and molecular data. It differs from Zygosepalum in the cespitose habit, the erect inflorescences, the entire clinandrium, and the subtriangular stipe of the pollinarium. Species assigned to the new genus are generally found on sandstone mountains above 1000 m (“cerros” and “tepuis”) of the Guayana Highlands. In contrast, plants of Zygosepalum s.s. bear arching inflorescences, the flowers have a fimbriate clinandrium, the stipe of the pollinarium is subquadrate, and they are epiphytes in humid tropical forests of the Guayana, generally below 500 m.