Pear psylla, Cacopsylla pyricola (Förster), is the most economically challenging pest of commercial pears in Washington and Oregon, the top producers of pears in the United States. The objective of this study was to quantify economic injury levels and thresholds for pear psylla. We used the relationship between pear psylla adult and nymph densities, and fruit downgraded due to psylla honeydew marking to identify injury levels. We calculated economic injury levels using the cost of downgraded fruit and average management costs (spray materials and labor). Using economic injury levels, we determined economic thresholds for pear psylla, which include predicted pest population growth, natural enemy predation, and anticipated delays between when pest populations are measured and when managers apply interventions. Economic thresholds generated by this study were 0.1–0.3 second-generation nymphs per leaf and 0.2–0.8 third-generation nymphs per leaf depending on predicted price and yield for insecticide applications at 1,300 pear psylla degree days in the second generation and 2,600 pear psylla degree days in the third generation. Natural enemy inaction thresholds identified by this study were 6 Deraeocoris brevis or 3 Campylomma verbasci immatures per 30 trays or 2 earwigs per trap for third-generation optional insecticide applications.